2024 Phosphatase and actin regulator 1

Phosphatase and actin regulator 1

Author: xzvv

August undefined, 2024

WebApr 13, 2024 · IntroductionObscurin (720–870 kDa) is a giant cytoskeletal and signaling protein that possesses both structural and regulatory functions in striated muscles. Immunoglobulin domains 58/59 (Ig58/59) of obscurin bind to a diverse set of proteins that are essential for the proper structure and function of the heart, including giant titin, novex … WebMar 21, 2024 · PHACTR1. phosphatase and actin regulator 1. Gene ID: 221692, updated on 8-Dec-2024. Gene type: protein coding. Also known as: RPEL; DEE70; RPEL1; EIEE70; dJ257A7.2. See all available tests in GTR for this gene. Go to complete Gene record for …

PHACTR1 phosphatase and actin regulator 1 [ (human)]

WebMay 1, 2024 · which may also play a role in regulation of the actin cytoskeleton. We refer to members of this family of proteins as phosphatase and actin regulators (phactr) 1–4 based on their putative func-tional roles. Materials and Methods Yeast Two-Hybrid Screening, cDNA Expression, and Coimmunoprecipi-tation. WebAug 13, 2014 · The PHACTR1 gene encodes the protein phosphatase 1 and actin regulator 1 (PHACTR1), an enzyme regulating endothelial nitricoxide in humans . PHACTR1 has been demonstrated to be an important modulator in the pathophysiology of cardiovascular disease [ 9 ], and it may be involved in the formation of stenosis in cardiac vessels of CAD … senior software engineer jobs from home

Activation of protein phosphatase 1 by a small molecule

WebNov 1, 2024 · The human phosphatase and actin regulator 1 (PHACTR1) may be involved in such diseases, but its precise regulatory function remains unclear due to the large number of potential interaction partners. The same phenomenon makes this protein difficult to express in mammalian cells, but it is also an intrinsically disordered protein that likely ... WebFeb 26, 2010 · Protein dephosphorylation at the serine and threonine residues of various proteins, similar to their cognate phosphorylation, has important roles in regulating … senior software engineer lockheed salary

PHACTR1 phosphatase and actin regulator 1 - Gene - GTR - NCBI

Protein phosphatase-1 regulates Akt1 signal transduction …

WebApr 7, 2024 · PHACTR-1 (Phosphatase and Actin Regulator 1) Deficiency in Either Endothelial or Smooth Muscle Cells Does Not Predispose Mice to Nonatherosclerotic … WebApr 10, 2024 · Axon pathfinding is an essential step in neuronal network formation. Shootin1a is a clutch-linker molecule that is mechanically involved in axon outgrowth and guidance. It was previously shown that concentration gradients of axon guidance molecule netrin-1 in the extracellular environment elicit asymmetrically localized Pak1 kinase … senior software engineer salary at microsoftWebNov 18, 2014 · The current hypothesis suggests that the phactr–PP1 complex is controlled by the changes in the cytoplasmic G-actin concentration, which regulate the actin cytoskeleton dynamics by modulating the phosphorylation status of … senior software engineer salary houston

"WebPhosphatase and actin regulator-1 (PHACTR-1) is highly expressed in endothelial cells and neurons (Allen et al., 2004). PHACTR-1 is thought to regulate synaptic plasticity by modulating protein phosphatase 1 (PP1) activity, and it is important for neuronal activity (Ceulemans and Bollen, 2004). " - Phosphatase and actin regulator 1

Phosphatase and actin regulator 1

WebMay 1, 2024 · Protein phosphatase 1 (PP1) is a multifunctional enzyme with diverse roles in the nervous system, including regulation of syn-aptic activity and dendritic morphology. … WebApr 4, 2024 · PHACTR1 phosphatase and actin regulator 1 [ (human)] Gene ID: 221692, updated on 2-Oct-2024 Summary The protein encoded by this gene is a member of the …

Did you know?

WebFree shipping on catalog antibody and protein orders over $999. More>> WebApr 23, 2004 · Protein phosphatase 1 (PP1) is a multifunctional enzyme with diverse roles in the nervous system, including regulation of synaptic activity and dendritic morphology. …

WebApr 23, 2004 · Protein phosphatase 1 (PP1) is a multifunctional enzyme with diverse roles in the nervous system, including regulation of synaptic activity and dendritic morphology. PP1 activity is controlled via association with a family of regulatory subunits that govern subcellular localization and substrate specificity. WebPhosphatase and actin regulator-1 (PHACTR-1) is highly expressed in endothelial cells and neurons (Allen et al., 2004). PHACTR-1 is thought to regulate synaptic plasticity by …

WebOct 11, 2024 · Studies have found that the phosphatase actin regulatory factor 1 expression can be related to stroke, but it remains unclear whether changes in phosphatase actin regulatory factor 1 expression also play a role in traumatic brain injury. WebJul 23, 2024 · Neuron-enriched phosphatase and actin regulator 3 (Phactr3)/ nuclear scaffold-associated PP1-inhibiting protein (Scapinin) regulates dendritic morphology via …

WebApr 20, 2014 · Phosphatase and actin regulator 4 (Phactr4) is a newly discovered protein that inhibits protein phosphatase 1 and shows actin-binding activity. We previously found that Phactr4 is expressed in the neurogenic niche in adult mice, although its precise subcellular localization and possible function in neural stem cells (NSCs) is not yet …

WebAbstract Background: Some genetic association studies tried to investigate potential associations of phosphatase and actin regulator 1 (PHACTR1) polymorphisms with coronary artery disease (CAD). However, the results of these studies were not consistent. senior software engineer raytheon salaryWebNov 25, 2024 · The PHACTR1 gene belongs to a family of proteins that interact with actin and play a role in the regulation of cell morphology and motility. PHACTR1 is expressed in … senior software engineer salary dallasWebNCBI Full Gene Name phosphatase and actin regulator 3; NCBI Gene Aliases 1500003N10Rik, 4930415A02Rik, H17739, Scapin1, Scapinin, mKIAA4224, s; Primer Type Gene-specific Primers; Add to Compare List. OriGene Technologies. 9620 Medical Center Drive # 200 Rockville, Maryland 20850. United States Phone: 1-888-267-4436 (U.S. only) / … senior software engineer paid per hourWebphactr1 phosphatase and actin regulator 1 [ (zebrafish)] Gene ID: 100334776, updated on 3-Dec-2024 Summary Predicted to enable actin binding activity; protein phosphatase 1 binding activity; and protein phosphatase inhibitor activity. … senior software engineer salary in pakistanWebFeb 22, 2024 · (1) Ezrin is a general cross-linker which binds membrane proteins such as receptors, ion channels, and transporters to the actin cytoskeleton directly or indirectly through scaffold proteins. It also connects the extracellular matrix to the actin cytoskeleton. (2) Ezrin functions as a regulator of G-protein-related proteins. senior software engineer resume exampleWebApr 26, 2013 · Furthermore, we identified PHACTR1, an actin-binding protein, to be positively regulated by TGF-β in a miR-584-dependent manner. Moreover, we found TGF-β-mediated down-regulation of miR-584 and increased expression of PHACTR1 to be required for TGF-β-induced cell migration of breast cancer cells. senior software engineer salary in pricelineWebIntroduction. According to the latest data from the International Diabetes Federation, more than 382 million people are suffering from diabetes in 2013, and by 2035, this number will reach a staggering 592 million, causing 4.6 million deaths each year. 1 Type 2 diabetes mellitus (T2DM) is the most common form and accounts for around 90% of all diabetes … senior software engineer salary at google