Creb ser-133
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Creb ser-133
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Webtion of the cAMP response element binding protein (CREB), a transcriptional factor, may regulate hypothalamic circadian rhythms in the brain. Here, we investigate the circadian regulation of CREB and Ser-133-phospho-CREB (PCREB) in the mouse esophagus by immunocytochemical and biochemi-cal methods. We found that, during the dark phase, … WebThe PathScan ® Phospho-CREB (Ser133) Sandwich ELISA Kit is a solid phase sandwich enzyme-linked immunosorbent assay (ELISA) that detects endogenous levels of CREB when phosphorylated at Ser133. A CREB rabbit antibody has been coated onto the microwells. After incubation with cell lysates, CREB protein (phosphorylated and …
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WebFeb 20, 2001 · A leading paradigm of such regulation is the activation of the nuclear transcription factor CREB, the Ca 2+ - and cAMP-responsive element binding protein ().CREB becomes activated when phosphorylated on Ser-133 and, through interaction with its nuclear partner CREB-binding protein (), drives the transcription of a large number of … WebCREB binding protein (CBP), a transcriptional coactivator that directly interacts with CREB, binds to CREB in the region of serine 133. CREB is involved in different cellular processes including the synchronization of circadian rhythmicity, differentiation of adipose cells, and learning and memory. In humans, the gene is located on the q arm of ...
WebDownload Zoom Anti-phospho-CREB (Ser133) Antibody, clone 10E9 is a Mouse Monoclonal Antibody for detection of phospho-CREB (Ser133) also known as active transcription factor CREB & has been validated in WB, ELI More>> MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. …
WebAug 30, 2024 · There are three phosphorylation sites existing in the amino-terminal of CREB, and the phosphorylation of Ser133 is the most studied. The phosphorylation of Ser133 leads to a 10- to 20-fold increase in … bauke adriaanseWebCREB is activated by phosphorylation at Ser133 by various signaling pathways including Erk, Ca2+, and stress signaling. Some of the kinases involved in phosphorylating CREB at Ser133 are p90RSK, MSK, CaMKIV, PKA and MAPKAPK-2. All Application Notes Scientific Presentations Flyers Posters Technical Notes Guides Videos Product Insert Catalog bau kebakaranWebCREB serine 133 (Ser-133) residue is phosphorylated by various kinases and this phosphorylation promotes the interaction of CREB with a number of transcription coactivators, especially the histone acetyltransferases CREB … tim ipadWebThe cell-based assays presented in Figure 2 showing that serotonin favors CREB phosphorylation on Ser 133 suggested that CREB is a transcriptional mediator of serotonin regulation of bone mass in VMH neurons. To establish formally that this is the case in vivo, we first deleted Creb in VMH neurons (Creb Sf1 −/− mice). tim ipad pro a rateWebThis ChIPAb+ Phospho-CREB (Ser133) -ChIP Validated Antibody & Primer Set (Antibody ChIP) conveniently includes the antibody & the specific control PCR primers. Key … bauke hagaWebSep 13, 2001 · Cyclic AMP regulates the expression of numerous genes through phosphorylation of CREB at Ser 133, mediated by protein kinase A (PKA) 5.The ability of CREB to stimulate the gluconeogenic PEPCK … tim ipad pro 12.9WebThe cells were lysed and quantified for gene-specific Bax and Bcl2 mRNA. In separate experiments, cells were incubated with C5a for 5-30 min with, or without, pretreatment with wortmannin, PD98059, or alkaline phosphatase. Cells were then lysed and immunoblotted using antihuman phospho-CREB (Ser133) antibody. bau kecoa